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May 09, 2022 2 min read

There are a few things that most people know about marijuana. One of them is the fact that it has certain medicinal effects. That is one of the primary reasons why medical marijuana is legal in a variety of states. However, another thing that quite a few people know about marijuana is the fact that it contains both THC and CBD.

These are the most commonly known cannabinoids in marijuana and they are important to keep in mind. Despite this, it is a fact that hemp contains many other cannabinoids besides just THC and CBD. Cannabinoids can also work together and this leads to them having enhanced effects. Continue reading for more information about this process and how it can improve CBD oil.

Entourage Effect 101

It is crucial to begin by talking about the Entourage Effect. Simply put, the Entourage Effect is the term that describes how multiple compounds work together in a synergistic way rather than working alone, which then enhances the effects of cannabinoids. As previously mentioned, this effect refers to all the cannabinoids, not simply CBD and THC. You can think of it like two sports teams, one of which has one player doing everything and the other which has everyone contributing equally. Naturally, you would expect the team with everyone contributing equally to win, in this case.

Some Hemp Extracts Are Better Than Others

It is important to keep in mind the fact that some hemp extracts are superior to others. If two companies both make CBD oil, that doesn't mean that the CBD oil from each company is equal in either quality or effectiveness. Simply put, not all hemp extracts are created equal. Quite a few variables are relevant when a company manufactures CBD extracts. The company's purification process, the parameters of the extraction method, the extraction method itself, and the genetics of the hemp plants all play a part in manufacturing CBD extracts.

What Does Research Say About the Entourage Effect?

The idea of the Entourage Effect first began in 1998. Professors Shimon Ben-Shabat and Raphael Mechoulam discovered that the endocannabinoid system displayed an entourage effect upon noticing that the plant compounds increased our receptors' activity significantly. These receptors are crucial in a variety of body functions, like sleep cycles, communication between cells, memory, and many others. A 2001 paper by Ethan Russo and John McPartland, two well-respected researchers, describes that terpenes enhance cannabinoids' effects. The paper also states that terpenes interacting with cannabinoids makes a notable difference in the effects of those cannabinoids.

How Does The Entourage Effect Improve CBD Oil?

Simply put, the Entourage Effect improves CBD oil in that it enhances the effects of the cannabinoids found in CBD oil. This is clear when you compare a CBD product that has fewer compounds to one that includes terpenes and cannabinoids. It is even more clear if you compare a CBD product that only includes pure CBD to a CBD product with a variety of compounds. In any case, the Entourage Effect is a notable example of the benefits of synergistic cooperation between compounds.


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