February 17, 2021 4 min read

With a wide range of benefits, including relieving pain and anxiety and protecting your heart and nervous system, the best Cannabidiol (CBD) dosages vary. Here is what research reveals so far about how much CBD to take.

Based on studies and clinical experience with the CBD medication Epidiolex, the medically recommended dosage for CBD is as follows:

  1. Start with .25 milligrams per two pounds of body weight (mg/lbs) two-three times a day.
  2. After one week, increase the dose by 5 – 10 mg. Optimal dose for serious conditions is 1mg per 2lb of body weight 3 x per day. 
  3. Keep a written or verbal record of your initial symptoms, dosage, and progress.
  4. Gradually adjust dosage up to 5mg/2lbs of body weight two times a day.
For example, a person who weighs 150 pounds would start with two daily doses of 20mg and could gradually build up to 375 mg twice a day or 250mg 3 x per day if needed. As with any drug, the appropriate dosage for CBD provides a therapeutic effect and is well-tolerated.

Managing your dose is easy with Jampha’s organic, full-spectrum CBD oil. The droppers are clearly marked, and each one-milliliter dropper contains 20mg-50mg of CBD.

CBD is safe to use and usually has little to no side-effects. However, if you have liver damage, a medical condition, or take prescribed medication, it is crucial to consult your doctor before taking CBD.

Dosage Recommendation by Condition:

Legal for medical use in the U.S. since 2018, CBD’s benefits, mechanisms, and ideal dosage are still under investigation. Here are a few of the studies so far, showing the range of doses that worked for specific conditions.

Condition CBD Dose Form Taken
Anxiety 25–600 mg Oral
Type 2 diabetes 100 mg twice daily Oral
Pain due to cancer 50–600 mg per day Oral
Parkinson’s disease 75–300 mg per day Oral
Huntington’s disease Up to 12 sprays per day Sativex nasal spray (contains CBD and THC in 1:1 concentration)
Psychotic symptoms 200–800 mg daily Oral
Inflammatory skin conditions 2-3 x/day for 3 months Topical gel
How Long Does It Take to See Results with CBD?

While some people feel benefits 15 to 20 minutes after taking CBD, the best results come from consistent use over several months. CBD is fat-soluble and builds up in your body over time, becoming more effective.

Jampha has found that 90 dosing protocols as directed by your doctor are accross most situations the best formal dosing plan to see the best long term results. 

The relationship between CBD and our body is complicated. Cannabidiol is a pleiotropic drug, which means it produces many effects through multiple molecular pathways. So far, science identifies more than 65 molecular targets of CBD inside the human body.

CBD can:
  • Interact with cannabinoid receptors CB1 and CB2 without binding to them
  • Modulate various non-cannabinoid receptors and ion channels
  • Act through receptor-independent pathways to modulate reuptake of specific neurotransmitters or enhance/inhibit the binding action of receptors

If you’re new to CBD, it’s wise to give yourself three months to track dosage and progress so you can accurately assess its benefits.

What Influences My CBD Dose?

How long and consistently you take CBD will impact its effectiveness, but other things can influence your ideal dosage as well.

Your body weight, metabolism, current health, and other medications you use can change how much CBD you need for the results you want.

For example, people who exercise regularly metabolize fat faster. Since CBD is fat-soluble, people with a lower density of fat cells will find CBD’s effects to wear off more quickly.

Is CBD Safe in High Doses?

Two research reviews, one in 2011 and the second in 2017, found continuous use of CBD is tolerated well by humans even at high doses of 1,500 mg a day.

However, the best practice is to start with a small CBD dose and build over time until you are satisfied with the effect. Some patients and conditions respond better to smaller doses, so more CBD is not always better.

CBD’s Side-Effects:

Only a small percentage of CBD users experience side-effects. They may include:

  • Drowsiness
  • Irritability or agitation
  • Digestive issues like diarrhea or appetite changes
  • Interactions with other medications

If you experience side-effects, reduce or stop your dose and let your doctor know what happened.

Third-Party Tested CBD Sourced from U.S. Grown Hemp:

At Jampha, we understand the quality of your CBD impacts the benefits you get. We create our solvent-free CBD oils and topicals from organic hemp grown in the United States.

Each product combining high quality organic CBD distillate with Synergy Enhanced Terpene Infusionsutilizing organic plant terpenes to add to the full-spectrum benefits.

Our products are third-party tested, so you know exactly what you’re getting with each dose.

Science’s understanding of how CBD works with the human body is just beginning to take form. It is an all-natural medicine but also powerful, so a systematic and conscious approach to dosage is the best path to your desired benefits.

                                                Maitreya Loving-Kindness

Disclaimer Notice: 

Because Tibetan treatments, therapies and medicine are not yet recognized, licensed, or regulated by the AMA or FDA or any US agency. This document is not to be construed as a diagnostic tool and/or that of prescribing medicines or therapies, it is for informational support only. Consult your doctor before taking any medications.

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